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however, in the case of injury or disease, loss of NMNAT activity leads to NAD + depletion and NMN accumulation, which in turn activates SARM1 53,54,289

Supplementary information Supplementary Fig

Clinical protocols for specific therapeutic applications use infusion windows as short as 15 minutes

Furthermore, administration of Fer-1 effectively rescued oxalate-induced lipid peroxidation, manifested by decreased MDA levels and reduced 4-HNE production (Fig