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They found that iron, ACSL4, and MDA levels increased with increasing reperfusion time, with concomitant decreases in GPX4 levels, and deferoxamine treatment significantly ameliorated myocardial injury [88]

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Integrating these approaches may offer a more comprehensive strategy for managing the multifaceted pathology of diabetes As understanding of oxidative stress, inflammation, and immune dysfunction in diabetes deepens, personalized treatment strategies tailored to individual oxidative and inflammatory profiles may emerge as a new standard of care