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It is interesting to note that the positive effect of tirzepatide on body weight is associated with a significant improvement in quality of life and physical performance [50] and is independent of sex [51], baseline body mass index (BMI) [52] and potential side effects, predominantly gastrointestinal [53]

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Tirzepatide has shown to have anti-inflammatory, metabolic, and cardiovascular effects that could be promising to long Covid patients. One published study found that in 47 people with mast cell activation syndrome, or MCAS, a condition in which white blood cells release inflammatory chemicals, 89 percent benefited from a GLP-1, especially at low doses