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Senolytic drugs: from discovery to translation Kirkland JL, Tchkonia T Journal of Internal Medicine (2020) This comprehensive review from the Mayo Clinic's leading senescence researchers places FOXO4-DRI within the broader context of senolytic drug development and clinical translation

Acts as a potent endogenous antioxidant, regulating pro- and anti-inflammatory pathways, and protecting against DNA damage and lipid peroxidation

These peptides not only protect keratinocytes (the dominant cells in the outer skin layer) from harmful UVB radiation but also activate genes for DNA repair

The combination allows for the evaluation of additive versus synergistic effects in preclinical obesity models