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Investigation of heterogeneity Our results showed that there was no significant between-study heterogeneity for studies measuring GSSG concentrations, whereas the other 34 oxidative stress-related markers showed significant between-study heterogeneities

This work has been widely read as evidence that neuroinflammation is a driver of neurodegeneration rather than merely a downstream marker, although that interpretation remains the subject of active investigation

The biggest differences are nail changes, swollen fingers or toes, and the presence of psoriasis