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Whos a candidate and who isnt FDA labels for the weight-loss indication require a BMI of 30 or higher, or a BMI of 27 or higher with at least one weight-related comorbidity (type 2 diabetes, hypertension, dyslipidemia, obstructive sleep apnea, or established cardiovascular disease)

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Liver steatosis results from an excessive delivery of FFAs from adipose tissue into the liver accompanied by insufficient lipid degradation as well as from an imbalance between the new lipid synthesis and catabolism

The exact mechanisms of these actions are not well-understood, although it appears that policosanol inhibits the production of cholesterol in the liver