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1 Researchers acknowledged the genetic effect on weight loss was relatively small but said the findings lay the foundation for precision medicine approaches to obesity treatment by providing direct evidence that variation in drug-target genes contributes to differences in how patients respond

Here, a luminescent-based assay was applied to CuCl-treated HepG2 and HepG2 ATP7B-KO cells, in which RLU are proportional to HO levels (Fig

Interestingly, one of the AGL patients with perilipin-1 antibody also had a mutation in the AIRE gene that causes autoimmune polyendocrine syndrome type 1 (APS1) (88)