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Given that SZ patients also experience loss of gut microbiota homeostasis, targeting the TLR4 signaling pathway and focusing on bacterial translocation and microbiota may offer new avenues for immunomodulatory therapy in schizophrenia

Although the specific genes and pathways may vary, differential DNA methylation in pediatric under- and overnutrition affect genes regulating similar metabolic processes and result in similar disease outcomes

It is still unclear whether dysbiosis acts as a driver, a consequence, or both

Response: We would like to clarify that we are not making any changes to the requirements currently in place for the supervision policy for teaching physicians