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Cameron, A

and physiology 46 (8), 780787

Research indicates that in healthy individuals, the gut microbiota is composed of approximately 40%-60% Firmicutes, 30%-40% Bacteroidetes, and 5%-10% Actinobacteria, while the proportion of Proteobacteria is relatively low ( 7,000 participants in 55 RCTs, the relative risk of any adverse event was not increased versus placebo, but adverse-event reporting is inconsistently captured and often under-classified, limiting firm safety conclusions (137)