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Whilst leptin resistancea condition where the brain fails to respond to satiety signalsis commonly associated with obesity, GLP-1 agonists are not specifically indicated for treating this phenomenon

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Research carried out in 2007 emphasized its usefulness as a treatment for post-traumatic stress disorder (PTSD), showing a significant decrease in symptom severity among participants

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More significant changes in fat distribution tend to happen after a couple of months of continued use and lifestyle support

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