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Pro-inflammatory cytokine levels, such as IL-6 and tumor necrosis factor (TNF-), are elevated in the serum and cerebrospinal fluid of patients with depression (Haapakoski et al., 2015)

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However, in the presence of laccase, glutathione and Metschnikowia pulcherrima were not effective enough to adequately prevent the grape juice from browning

For example reactions requiring GSH as a key cofactor are catalyzed by the prostaglandin H synthase, the rate-limiting enzyme in the production of prostaglandins and thromboxane [25], which are essential regulators of vascular function