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More specifically, we will discuss the current methods of neurotherapeutic brain stimulation such as DBS, experimental and clinically relevant methods such as transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), and theta burst stimulation (TBS), and emerging methods of stimulation such as optogenetics, near-infrared, and magnetothermal DBS

For gut-related applications, oral delivery has a stronger scientific rationale because the compound makes direct contact with GI tissue

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