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"That 37% is an average regain of the weight lost, so that's also an optimistic way to look at it, because that means you've retained about 63% of your weight loss." How much weight someone will regain after stopping weight-loss medications and the speed at which it comes back will vary from individual to individual
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NICE recommends semaglutide for weight management only within specialist weight management services and under more restricted BMI criteria than the MHRA licence
The drug also lowers cholesterol, reduces CRP inflammation markers, decreases blood pressure, and may preserve muscle better than earlier GLP-1 medications creating comprehensive metabolic benefits beyond just weight reduction
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