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(10) Also excluded were those who had received liver function-enhancing medications, antibiotics, choleretic agents, antioxidants, or dietary supplements within 14 days of the first dose of the investigational product, or who did not agree to abstain from such medications from 14 days to the end of the study, (11) and those who had received drugs that induce or inhibit drug metabolizing enzymes, such as barbiturates, within 30 days of the first dose of the investigational product, or who did not agree to abstain from such drugs from 30 days to the end of the study

doi: 10.1039/C5FO01342A 143 LinY

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The oral form of NAC (trade name Mucomyst) is the antidote formulation of choice and is used for the treatment of acute, chronic, or late-presenting toxic acetaminophen ingestions