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Notes 8 , 18 (2015)

Table S3)

In some embodiments, the formulations or compositions described herein are liquids and are administered via narrow gauge needles or cannulas (e.g., 22 gauge needle, 25 gauge needle, or cannula), minimizing damage to the tympanic membrane upon administration

Cancer Research Applications Glutathione presents a complex dual role in cancer research: Tumor Cell GSH Levels: Investigation of elevated GSH in cancer cells and implications for cell proliferation Chemotherapy Resistance: Studies on GSH-mediated drug resistance mechanisms in tumor cells GSH Depletion Strategies: Research on buthionine sulfoximine (BSO) and other GSH-depleting agents to sensitize tumors Radiation Sensitivity: Examination of GSH status and radiation-induced oxidative damage in tumor vs