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In patients with Polycystic Ovary Syndrome, to what extent do you feel that the benefits of GLP-1 receptor agonists are attributable to weight loss (versus their direct effects on insulin resistance, androgen levels, and ovarian function)

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[1] Allergic reactions range from local injection site reactions (erythema, swelling, pruritus) to serious systemic symptoms including generalized urticaria, angioedema affecting the face or throat, respiratory difficulty, and anaphylaxis with cardiovascular collapse