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In addition, quercetin has been reported to exert similar protective effects by activating the Nrf2/HO-1 signaling pathway, enhancing antioxidant enzyme expression, and mitigating hydrogen peroxide-induced oxidative stress in keratinocytes (Jafarinia et al., 2020)

When consumed in standard capsule or tablet form, glutathione is rapidly broken down by digestive enzymes and stomach acid before it can reach systemic circulation

One key process is glutamate excitotoxicity, where a buildup of glutamate at the synapse due to reduced function of the transporter EAAT2 (also known as GLT-1) leads to overstimulation of N-methyl-D-aspartate (NMDA) receptors

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