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With careful dose increases, close medical follow-up, and clear guidance on nutrition and hydration, most patients find that these symptoms ease as their body adjusts

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Falster says the main problem with these medications is that when you lose weight, you lose muscle and some bone density along with the fat and when you go off them, and you put fat back on, you don't regain muscle or bone, so you can end up weaker and more fragile, as well as back at your old weight

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