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10.1056/NEJMcp1113996 [DOI] [PubMed] 3.Carmel R (2000) Current concepts in cobalamin deficiency

The growth and survival of a cell depend on reactive oxygen species (ROS) homoeostasis

Clinical studies have used schedules more intensive than those seen in recovery practice: patients with Parkinson's disease received 1,400 mg three times a week for four weeks (Hauser et al., Movement Disorders 2009, PMID 19230029), while studies on skin lightening used 1,200 mg twice a week for six weeks (Alzahrani et al., Cureus 2025, PMID 40013212)

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