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Among these molecules, activation of CREB and inhibition of GSK-3 and FoxO1/O3 are likely to participate in the neuroprotective activities of insulin, IGF-1, and GLP-1 toward DRG neurons ( FIGURE 1 Although there have been no reports regarding the efficacy of GLP-1RA for oligodendrocyte function in vitro , growing evidence with Schwann cells may be applicable to CNS myelination in the future

10.1038/s41418-019-0393-7 30 ChenP.LiX.ZhangR.LiuS.XiangY.ZhangM.et al (2020)

Schizophrenia Research, 190 , 1827