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Collagen-Derived Dipeptides (Pro-Hyp, Hyp-Gly): The Underrated Workhorse Hydroxyproline-containing dipeptides from hydrolyzed collagen survive intestinal digestion and are detected in human plasma after oral collagen ingestion (Iwai et al., 2005, J

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Lipotropic injections are generally not recommended during pregnancy or breastfeeding, for people with a known allergy to any component of the formulation (including B12/cobalt), for those with certain kidney or liver conditions, or for those with certain medical conditions

There is insufficient evidence for the use of B12, beyond correction of deficiency, in cognitive impairment, depression and fatigue