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In addition, genes involved in TG synthesis and lipolysis (for example, Gpat3, Lpin1/2, Plin5 , and Ces1d/b ) were downregulated in the livers of SLC25A45 KO mice, whereas fatty acid synthesis and elongation (for example, Acacb, Elovl1,2,6 ) were upregulated in the SLC25A45 KO livers ( Fig

Selective deletion of the leptin receptor in dopamine neurons produces anxiogenic-like behavior and increases dopaminergic activity in amygdala

This may support better glucose regulation and metabolic health

Research should explore novel delivery and accessibility, in addition to larger trials investigating clinical and cost effectiveness