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Genistein and/or sulfasalazine ameliorate acetic acid-induced ulcerative colitis in rats via modulating INF-/JAK1/STAT1/IRF-1, TLR-4/NF-B/IL-6, and JAK2/STAT3/COX-2 crosstalk

Given the reduced efficacy of GLP-1RAs on glycaemia and the reported association of genetic variation in PAM with BMI we sought to establish whether the reduced efficacy extended to effects on weight loss in the two studies (PRIBA and GSK-Harmony) where data were available following 6 months of treatment (Additional file 2: Fig

Multiple human interventions with inulin, fructooligosaccharides and resistant starch have shown shortterm increases in GLP1 or GLP1related markers

doi: 10.1016/j.exger.2009.12.004