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If youre not sleeping well, your circadian rhythm can get thrown off, and this can lead to digestive problems like constipation

doi: 10.1016/j.ejmech.2022.114324 15 Juarez-SaldivarABarbosa-CabreraELara-RamirezEEPaz-GonzalezADMartinez-VazquezAVBocanegra-GarciaVet al

GLP-1 medicines may have anti-inflammatory effects Researchers are also studying whether GLP-1 medicines may directly affect immune cells and inflammatory pathways

They also report a familiar list of issues that prescribers see in trials: severe nausea during titration, persistent fatigue, raised heart rate, and a burning skin sensation that researchers call dysesthesia