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When Supplements Are Not Enough Signs of underlying medical conditions ED plus chest pain, breathlessness, leg pain with walking ED with numbness, nerve symptoms, or major stress symptoms ED with persistent low libido and fatigue When to Consider Medical Treatment If no meaningful improvement after 3-6 months of consistent effort, or if symptoms worsen

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Makary and Prasad, both of whom are no longer with the agency, had previously objected to the drug, stating the data were insufficient for a marketing application