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2.1.3 Inhibited pyroptosis and inflammation of follicular granulosa cells Furthermore, researchers have discovered that metformin has the potential to enhance follicle development and induce ovulation by suppressing pyroptosis and inflammation of follicular granulosa cells
SCFAs, particularly butyrate, are known to support epithelial and BBB integrity and regulate microglial homeostasis, whereas altered microbial composition in PD may shift metabolite profiles toward a more pro-inflammatory state [123]
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