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Clinical trials of sodiumglucose cotransporter 2 (SGLT2) inhibitors and glucagon-like peptide 1 (GLP1) receptor agonists have shown beneficial effects of these agents on kidney outcomes in patients with type 2 diabetes mellitus

This approach preserves lean muscle while the peptide enhances fat burning

Many clinicians prescribe both together because they activate complementary receptor pathways, producing synergistic GH release greater than either peptide alone

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