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An independent clinical trial of LC supplementation in patients with osteoarthritis showed that LC significantly reduced serum levels of IL-1b and MMP-1 [157]

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Peptides were eluted from the column into the mass spectrometer using the following gradient: 1100% B in 65 min, 100% B for 20 min, 100 to 1% in 10 min, and finally 1% for 5 min