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Sunken cheeks, sagging skin, more visible fine lines and wrinkles can become more pronounced, especially if you are over 40

Several factors influence the choice of needle and syringe: Type of injection : Intramuscular (IM) or subcutaneous (SC) Gauge of the needle : Diameter of the needle Length of the needle : Determines the depth of injection Volume of the syringe : Determines the amount of B12 to be injected 3

Use caution if you have liver or kidney disease, bipolar disorder, seizure disorders, or if you take medications that affect methylation or neurotransmitters