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This is particularly important for people with underlying conditions, such as kidney disease or a history of thyroid issues

Patients interested in participating in legitimate clinical research, including trials of investigational medicines such as retatrutide, can search for opportunities via the NIHR's Be Part of Research portal (bepartofresearch.nihs.ac.uk)

For example, taking your weekly semaglutide injection on a Friday night might allow you to weather any weekend GI side effects at home rather than on a workday

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