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[30] The tudei cultivars may be easier and cheaper to grow: while it takes up to 5 years for noble kava to mature, non-noble varieties can often be harvested just one year after being planted

The most widely used consensus, that of the ADA/EASD, ranks SUs as the last option for patients with established cardiovascular or renal disease, and suggests that they should only be prioritized when cost is an issue [10]

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