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Serum creatinine and estimated GFR should be measured at baseline and again at four weeks post-switch

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The central research question this article addresses is straightforward but frequently misunderstood: what exactly does the Long R3 modification do at the molecular level, how does it alter the peptides half-life and receptor behavior, and how does IGF-1 LR3 differ from both native IGF-1 and the muscle-specific splice variant known as mechano-growth factor (MGF)