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Phase 3 results are needed No cardiovascular outcomes data available The biased signaling mechanism, while promising, needs long-term validation Exact molecular structure has not been publicly disclosed Phase 3 trials are planned but not yet enrolled Effects of CT-388, a once-weekly signaling-biased dual GLP-1/GIP receptor agonist, on weight loss and glycemic control in preclinical models and participants with obesity , published in Cell Metabolism (Roche/Genentech/Carmot Therapeutics investigators, 2025

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