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Once the diagnosis is confirmed, it is advisable to stop SGLT2i immediately and manage the patient with hydration and insulin therapy, correction of electrolytes with the same protocol followed for DKA

While a definitive, universally effective therapy remains elusive, ongoing research continues to expand the options available, fostering hope for more effective and personalized care in the future

The studies weve looked at have employed doses of glutamine as high as 40g per day with very few adverse effects.56 Glutamine has been effective in these studies at doses as low as 18-20g/day

These genes may serve as promising new targets for antidepressant therapy [246, 247]