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However, because of insufficient understanding of factors driving the aggressiveness of PTC, some highly aggressive PTCs do not receive timely treatment and develop into late-advanced or metastatic stages

DOI: 10.1002/14651858.CD015092.pub2 Tirzepatide for adults living with obesity by Juan VA Franco, Yang Guo, Lucia B Varela, Zakariya Aqra, Murad Alhalahla, Mauricio Medina Rodriguez, Edison Leonardo Salvador Oscco, Bernarda Patio Araujo, Susan Banda, Camila Micaela Escobar Liquitay, Javier Bracchiglione, Nicols Meza and Eva Madrid, 30 October 2025, Cochrane Database of Systematic Reviews

Errors at this step cascade through all subsequent calculations

Stechmiller, J