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E., Zhong, L

This class of medications has grown rapidly in the last couple of years, as both diabetes treatments like Ozempic, Mounjaro and Trulicity, and weight loss drugs, like Wegovy and Zepbound have found increased use

Step2 Preparation of L-3- cyano -2-hydrooxypropyl trimethylammonium L-3-chloro-2-hydroxypropyl trimethyl ammonium 50g was added in 250ml three-necked flask, dissolved in H2O (40ml), heated at 30C-70C, sodium cyanide (48g) was dripped, kept at 70C for 4 hours, evaporated under a reduced pressure, freezed below 0C, and dried to giveL-3-cyano -2 - hydroxypropyl trimethyl ammonium (43.8g), yield 92.1 %, m.p

As therapies become more powerful, personalization and long-term safety monitoring become even more critical