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Binge-like palatable food intake in rats reduces preproglucagon in the nucleus tractus solitarius

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This results in hepatocellular steatosis, endoplasmic reticulum structural damage due to phospholipid composition changes, and activation of the Bax and JNK/PUMA pathways, which increases TAG levels in hepatocytes and plasma

Zugail AS, Alshuaibi M, Lombion S, Beley S