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Periorbital wrinkles, hydration, and skin elasticity improved at 4, 8, and 12 weeks in the collagen supplement group compared with baseline or placebo-control values

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Our results showed that 10 M BAY 11-7082 effectively inhibited the nuclear translocation of NF-B p65 and the mRNA expression of Bax and P53 , but increased the mRNA expression of Bcl2 and Bcl-xL in the peroxynitrite + BAY 11-7082 group compared with the peroxynitrite-only group, as well as in the peroxynitrite + gpx1 / + BAY 11-7082 group compared with the peroxynitrite + gpx1 / group (Figures 9AC)

doi:10.1073/pnas.62.2.461