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When applied as eye drops, oxymetazoline, the active ingredient in Upneeq, activates alpha-adrenergic receptors in the Mllers muscle, causing it to contract and lift the eyelid

As a neuromodulator, Ang II stimulates ganglionic transmission and catecholamine release from adrenal medullary chromaffin cells and potentiated NE release from sympathetic nerve terminals in the periphery (177)

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In a clinical trial of people with Type 2 Diabetes, a group known to be deficient in glutathione, liposomal glutathione was given for three months