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Clinical Evidence Behind Semaglutide for Weight Loss The STEP (Semaglutide Treatment Effect in People with obesity) trials demonstrated that semaglutide produces average weight loss of 15% body weight over 68 weeks in non-diabetic adults, significantly outperforming diet and exercise alone

BMC Genomics 6 , 145, (2005)

Additionally, patients should have: A compatible device: An iOS or Google Play store compatible smartphone, tablet, or computer with a camera and microphone

Clinical trials show tirzepatide produces slightly greater average weight loss (around 2022%) compared to semaglutide (around 1417%) in similar populations