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This was attributed to the insulin group, which deviated from the other groups, making matching only possible for three of the four variables included in PSM (age, gender, pre-existing cardiovascular disease and heart failure) (Table 1)

Nevertheless, comparison between the two studied groups after 3 months follow up revealed no significant difference (P-value = 0.097)

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The collective results demonstrate that combined therapy of sCT and liraglutide significantly reduced food intake and body weight compared to vehicle and to a greater degree than the magnitude of food intake and body weight suppression observed after treatment with either mono-therapy alone (Fig