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How they work together Glutathione directly supports cellular antioxidant defenses, while vitamin C helps recycle glutathione back to its reduced, active state

Zhang X., et al., 2020 J Cell Physiol 235 (4):3425-3437

Incretin mimetics have demonstrated safety and efficacy in advanced kidney disease, however multiple studies have shown that use of GLP1-RA have shown improvements in glycemic control, body weight reductions, improved beta cell function, and decreased incidence hypoglycemia as compared to DPP4i in a general diabetes population 26,27,28,29,30,31 , effects which might explain the reduction of acute healthcare utilization observed in this study of patients with CKD treated with GLP1-RA as compared to DPP4i

That variation comes down to many factors, including age, baseline body composition, comorbid conditions, exercise, and the specific medication being used