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From colorful patches and fruit punch-flavored gummies to prebiotic powders and under-the-tongue tinctures, dietary supplements that claim to complement or supercharge the bodys levels of the gut hormone GLP-1 are a dime a dozen

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In the context of prolonged systemic administration, NMDA receptor antagonists, such as memantine and MK-801 (also known as dizocilpine), induce anorexia and weight loss in rodents 9,10,11