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Combination therapies that modestly lower ferroptosis thresholdsrather than forcibly collapsing antioxidant capacitymay provide a practical route to achieve efficacy with tolerable toxicity

Novo Nordisk noted it didn't sponsor this study and hasn't had the opportunity to evaluate the data, but said "we support research for potential advancements of treatments for patients with Type 1 diabetes as well as other serious chronic conditions." The company isn't pursuing trials of semaglutide for type 1 diabetes itself, "but we do continue to support investigator-initiated studies," a spokeswoman told CNN by email

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The underlying tissue is undergoing active remodeling