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Effects of Liraglutide Compared With Placebo on Events of Acute Gallbladder or Biliary Disease in Patients With Type 2 Diabetes at High Risk for Cardiovascular Events in the LEADER Randomized Trial

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While transient NF-B activation contributes to adaptive inflammatory responses, sustained ROS accumulation maintains chronic NF-B signaling, promoting muscle protein degradation, metabolic dysfunction, and inflammatory remodeling (Surai et al., 2021)

10.1073/pnas.1000154107 Proc