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If the solution seems thicker when drawn into a syringe compared to when it was fresh, aggregation has likely progressed substantially

The results obtained in the zwf1 strain further highlight the advantage of the oxidant recovery assay over the sole determination of steadystate OxD values as OxD[IMS] and OxD[cytosol] at steady state differed only slightly from the respective value in the wt

Dosage should start at 1 g/day (10 mL/day), and be increased slowly while assessing tolerance and therapeutic response