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In preclinical models with an acute diet-induced liver injury model due to a single high-dose fructose binge in mice, as well as a chronic mouse feeding model incorporating fructose intended to mirror early MASLD with features of steatohepatitis, Retatrutide reduced the expression of hepatic inflammation markers chemokine ligand-1 (Cxcl-1), serum amyloid A1 (Saa-1), and serum amyloid A2 (Saa-2) (53)

If youre not breastfeeding, Darji says GLP-1s are an option as long as your doctor prescribes them after a thorough assessment of your individual health status

Research continues to explore its biological effects and potential applications

Many people find smaller, more frequent meals easier when appetite changes (1)