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And all of a sudden, it's like it flipped and became a Republican issue, which is staggering to me

The difference lies in manufacturing (compounded via licensed 503A pharmacies) and pricing, not clinical effectiveness

Oxidative stress may impair this pathway, reducing its ability to suppress nociceptive transmission, thereby contributing to exaggerated pain responses in FM ( Lipid metabolism alterations and fibromyalgia Recent metabolomic studies have highlighted significant alterations in lipid metabolism in FM patients, particularly shifts in phospholipid composition (12)