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Mandatory geographic area means a CBSA or metropolitan division as defined by the Office of Management and Budget and selected by CMS under the terms of 512.710(f)

This method not only saves time by reducing the number of items that must be decontaminated or brought into the cleanroom, but also improves surface coverage, lowering the risk of missed spots or insufficient wetting during residue removal

To eliminate bias caused by the order of rows in the covariate matrix, the row order was randomized

In the United States, it is available for purchase online, but regulatory authorities do not sanction its use in humans