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To induce acute liver injury, 8-week-old NSI mice received two consecutive intraperitoneal injections of DMN (7 mg/kg, Sigma, 1.0% dissolved in saline)

BPC-157 is not an approved substance in these contexts

Usually, doses are between 1,000 to 2,500 mcg per shot

These are dependent on inflammasome activation following the detection of PAMPs which induces physiological changes in the cell including sloughing, cytokine secretion or coordinated cell death, each of which limit bacterial spread (Lamkanfi and Dixit 2017